Signature Button Not Working in Outlook 2013/2016

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In order to make the Signatures button work, try the following:

In these registry keys (for x64 and x86 Office editions respectively) change the values of the Default and LocalServer32 parameters to the full path to the outlook.exe executable file on your computer (for example, to C:\Program Files (x86)\Microsoft Office\Office16\Outlook.exe for Outlook 2016):


  • HKEY_LOCAL_MACHINE\SOFTWARE\Classes\Wow6432Node\CLSID\{0006F03A-0000-0000-C000-000000000046}\LocalServer32
  • HKEY_LOCAL_MACHINE\SOFTWARE\Classes\CLSID\{0006F03A-0000-0000-C000-000000000046}\LocalServer32